An attractive approach: Biogenic magnetic nanoparticles, so-called magnetosomes, containing a magnetic iron oxide core enclosed in a protein–lipid membrane, were chemically functionalized with DNA oligonucleotides by using a modular coupling approach. The resulting nanoparticles were used for the assembly of heterostructures with DNA-modified gold nanoparticles (see TEM image) and as reagents for protein detection.
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Ceyhan et al. (2006) studied this question.
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