Some Aspects of the Nature of the Chemical Changes Occurring in Atheromatosis

Article1 April 1941SOME ASPECTS OF THE NATURE OF THE CHEMICAL CHANGES OCCURRING IN ATHEROMATOSISIRVINE H. PAGEIRVINE H. PAGESearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-10-1741 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptVirchow was the first to recognize that atheromatosis might result from loosening of the connective tissue ground-substance, of which the arterial intima is for the most part composed, and subsequent infiltration with fat from the blood stream. The loosening of the ground-substance was believed to be caused by mechanical strain. Aschoff and Ribbert in particular have championed this so-called "infiltration theory."Aschoff1thought that the fatty material deposited in vessels consisted almost exclusively of cholesterol esters coming from blood plasma which nourished the vessel wall. 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CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Indianapolis, Indiana*Lecture presented before the Philadelphia Metabolic Association December 8, 1934.From the Lilly Laboratory for Clinical Research, Indianapolis City Hospital Indianapolis, Indiana. 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W. C.Cholesterol content of the coronary arteries and blood in acute coronary artery thrombosisArteriosclerosisThe Cholesterol Content of the Human Aorta in Relation to the Serum Cholesterol ConcentrationThe clinical significance of cholesterol 1 April 1941Volume 14, Issue 10Page: 1741-1755KeywordsBloodBlood plasmaCholesterolClinical laboratoriesConnective tissueFatsLipidsResearch laboratoriesRivers ePublished: 1 December 2008 Issue Published: 1 April 1941 Copyright & PermissionsCopyright, 1941, by The American College of PhysiciansPDF downloadLoading ...