Antibiotic-Disinfection Compatibility Studies in Solution Used for Dipping Turkey Hatching Eggs

A great number of turkey hatcheries are using tylosin tartrate in a dipping procedure to control egg transmitted Mycoplasma sp. (PPLO), primarily Mycoplasma meleagridis. A quaternary ammonium compound is commonly used as a sanitizer and solution preservative. A few hatcheries are including neomycin sulfate into egg dipping solutions with the hope of reducing the incidence of Gram-negative organisms which may be in or on hatching eggs. This paper presents evidence that neomycin is incompatible with the quaternary preservative.