April 15, 2020Science AdvancesOpen Access

O -GlcNAc transferase promotes influenza A virus–induced cytokine storm by targeting interferon regulatory factor–5

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Abstract

-GlcNAcylation regulates IRF5 function during IAV infection, highlighting the importance of glucose metabolism in IAV-induced cytokine storm.

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Wang et al. (2020) studied this question.

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-GlcNAcylation regulates IRF5 function during IAV infection, highlighting the importance of glucose metabolism in IAV-induced cytokine storm.