Diet Based on Food from the Colombian Andean Region Decreases C-reactive Protein, IL6, and Leptin in Women with Obesity

People with obesity develop low-grade chronic inflammation, which is characterized by a high serum concentration of inflammatory markers (CRP, IL-6, TNF-α, and leptin), which predisposes the development of chronic diseases. These markers can be modulated by a diet; therefore, a research project was developed to determine the effect of a diet based on foods available in the Colombian Andean Region, containing anti-inflammatory properties in obese women. A controlled study was conducted with 30 women. For eight weeks the experimental group received a diet based on food rich in fiber, polyunsaturated fatty acids, vitamins and polyphenols. The experimental group reduced the serum concentrations of CRP (p = 0.005), IL-6 (p = 0.013) and leptin (p = 0.004), in comparison with the control group. Therefore, the findings suggest that a diet based on foods available in the Colombian Andean Region with anti-inflammatory nutrients reduces CRP, IL-6 and leptin in obese women.