Association of (+)-catechin and catechin-(4α→ 8)-catechin with oligopeptides

NOE studies on the complexation of (poly) flavanoids with peptides containing proline residues in aqueous solutions reveal site specific approach directed by hydrophobic interaction of the aromatic rings of catechin and its dimer, catechin-(4α→ 8)-catechin, to conformationally accessible regions of peptides without strong preference for interaction with proline residues.