Nonactivated alcohols along with arene compounds are used in electrochemical dehydroxylative arylation for constructing C(sp 3 )–C(sp 2 ) bonds. The P III reagent undergoes single-electron anodic oxidation to form its radical cation, which reacts with the alcohol to produce an alkoxytriphenylphosphine radical. Through spontaneous β-scission of the phosphoranyl radical, the C–O bond is cleaved to form an alkyl radical species, which couples with the radical anion generated by cathodic reduction of the electron-poor arene to afford the dehydroxylative arylated product.
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Wang et al. (2022) studied this question.
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