Article1 April 1963Clinical Observations of Acute Friedländer PneumoniaFELICE MANFREDI, M.D., WALTER J. DALY, M.D., ROY H. BEHNKE, M.D., F.A.C.P.FELICE MANFREDI, M.D.Search for more papers by this author, WALTER J. DALY, M.D.Search for more papers by this author, ROY H. BEHNKE, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-4-642 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn recent years acute Gram-negative bacterial infections of the lung, among them Friedländer pneumonia, have received renewed attention. The incidence and severity of these infections appear to be increasing, probably in relation to the development of drug-resistant organisms (1-4). Morbidity and mortality from acute Friedländer pneumonia vary according to different authors, but it is generally accepted that early diagnosis and adequate therapy greatly reduce the number and the severity of the complications (5-16).At the onset the diagnosis of acute Friedländer pneumonia may be quite difficult. The "classical" history, temperature curve, appearance of sputum, leukocyte response, and radiologic findings have...References1. CUTTS M: Pneumonia due to gram negative bacilli. Rhode Island Med. J. 43: 388, 1960. MedlineGoogle Scholar2. WEISSEISENBERGALEXANDERFLIPPIN WGMJDHF: Klebsiella pulmonary disease. Amer. J. Med. Sci. 228: 148, 1954. CrossrefMedlineGoogle Scholar3. FINLANDJONESBARNES MWFMW: Occurrence of serious bacterial infections since introduction of antibacterial agents. JAMA 170: 2188, 1959. CrossrefMedlineGoogle Scholar4. KESSNERLEPPER DMMH: A comparative study of hospital and community gram negative rods. J. Lab. Clin. Med. 58: 835, 1961 (abstract). 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Ann. Intern. Med. 44: 1070, 1956. LinkGoogle Scholar12. JERVEYHAMBURGER LPM: The treatment of acute Friedländer's bacillus pneumonia. Arch. Intern. Med. (Chicago) 99: 1, 1957. CrossrefGoogle Scholar13. OLSSONROMANSKY RAMJ: Clinical findings and results of a therapeutic regimen in acute Friedländer's pneumonia. Ann. Intern. Med. 56: 801, 1962. LinkGoogle Scholar14. JOFFE N: Acute fulminating Friedländer's pneumonia. Clin. Radiol. 12: 286, 1961. CrossrefMedlineGoogle Scholar15. BULLOWACHESSFRIEDMAN JGJNB: Pneumonia due to bacillus Friedländeri. Arch. Intern. Med. (Chicago) 60: 735, 1937. CrossrefGoogle Scholar16. BAEHRSHWARTZMANGREENSPAN GGEB: Bacillus Friedländer infections. Ann. Intern. Med. 10: 1788, 1937. LinkGoogle Scholar17. RITVOMARTIN MF: The clinical and roentgen manifestations of pneumonia due to bacillus mucosus capsulatus (primary Friedländer pneumonia). Amer. J. Roentgen. 62: 211, 1949. Google Scholar18. KORNBLUM K: The roentgen-ray diagnosis of pulmonary infections with the Friedländer bacillus. Amer. J. Roentgen. 19: 513, 1928. Google Scholar19. FELSONROSENBERGHAMBURGER BLSM: Roentgen findings in acute Friedländer pneumonia. Radiology 53: 559, 1949. CrossrefMedlineGoogle Scholar20. RILEY EA: Idiopathic diaphragmatic paralysis. A report of eight cases. Amer. J. Med. 32: 404, 1962. CrossrefMedlineGoogle Scholar21. FINLANDLOVERUD MHI: Massive atelectatic collapse of lung complicating pneumococcus pneumonia. Ann. Intern. Med. 10: 1828, 1937. LinkGoogle Scholar22. SHAWPAULSONKEE RRDLJL: Mucoid impaction of the bronchi. A study of thirty-six cases. Amer. Rev. Tuberc. 76: 970, 1957. Google Scholar23. KIRBYWADDINGTONFRANCIS WMWSBF: Differentiation of right-upper-lobe pneumonia from bronchogenic carcinoma. New Engl. J. Med. 256: 828, 1957. CrossrefMedlineGoogle Scholar24. NACLERIO EA: Bronchopulmonary Diseases, Paul B. Hoeber, Inc., New York, 1957. Google Scholar25. EPSTEIN SS: Experimental Klebsiella pneumonia in mice with particular reference to periarterial changes. J. Path. Bact. 78: 389, 1959. CrossrefMedlineGoogle Scholar26. SALEWOOD LWB: Studies on the mechanism of recovery in pneumonia due to Friedländer bacillus. I. The pathogenesis of experimental Friedländer bacillus pneumonia. J. Exp. Med. 86: 239, 1947. CrossrefMedlineGoogle Scholar27. SMITHWOOD MRWB: Studies on the mechanism of recovery in pneumonia due to Friedländer bacillus. III. The role of "surface phagocytosis" in the destruction of the microorganisms in the lung. J. Exp. Med. 86: 257, 1947. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Indianapolis, IndianaFrom the Department of Medicine, Veterans Administration Hospital, and Indiana University School of Medicine, Indianapolis, Indiana.This investigation was supported by Public Health Service Grant H-6583, National Institutes of Health, Bethesda, Maryland.Requests for reprints should be addressed to Felice Manfredi, M.D., Veterans Administration Hospital, 1481 West 10th Street, Indianapolis 7, Indiana. 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SHULMAN, M.D., LEON A. PHILLIPS, M.D., ROBERT G. PETERSDORF, M.D., F.A.C.P.Atelectasis with Pneumonia A Pathophysiologic StudyALTON I. SUTNICK, M.D., LOUIS A. SOLOFF, M.D., F.A.C.P. 1 April 1963Volume 58, Issue 4Page: 642-653KeywordsAntibioticsGram negative bacterial infectionsHospital medicineMedical servicesMorbidityMortalityNecrosisPneumoniaSputumTemperature Issue Published: 1 April 1963 PDF DownloadLoading ...
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