The width, thickness, and areas of the spleen were obtained by abdominal computed tomography on 50 patients. Several simple linear equations were used to predict the splenic volume and were correlated with a previously published method for volume estimation based on summing areas of multiple contiguous scans. This was used as a standard and demonstrated an excellent linear correlation (r = 0.95) with an estimate based on a product of length and maximal width. Correlation was even better (r = 0.991) with an estimate based on length, maximal width, and thickness.
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Cools et al. (1983) studied this question.
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