All articles of this category A convenient four step procedure for the synthesis of 2,4-dihydroxy-2 H -1.4-benzoxazin-3(4 H )-one ( 6 ), a bioactive natural product from Gramineae, is described that avoids disadvantages of hitherto existing methods and affords 6 in 60% overall yield.
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Sicker et al. (1989) studied this question.