Why the study?
Does perforating radiofrequency energy compared to conventional needle puncture alter the histopathological tissue response during transseptal left heart access in a piglet model?
Population
15 piglets undergoing transfemoral cardiac catheterization
Comparison
Perforating radiofrequency energy using a newly… vs Conventional needle puncture (NP)
Design
Preclinical
Follow-up
1 hour (acute) and 1 month (chronic)
Authors
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RF perforation yields comparable preclinical tissue response to needle puncture; leaves open translation to human transseptal safety.
Does perforating radiofrequency energy compared to conventional needle puncture alter the histopathological tissue response during transseptal left heart access in a piglet model?
Perforating radiofrequency energy for transseptal access produces a similar extent of acute injury and comparable chronic healing to conventional needle puncture in a preclinical model.
Veldtman et al. (2005) studied this question.
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