Ca2+ induced the formation of aerial mycelia in Streptomyces ambofaciens. Its effect was inhibited by ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid, a Ca2+ specific chelating agent. A survey of 36 strains of actinomycetes showed that Ca2+ regulated aerial mycelium formation in 21 (58%) of them. The Ca2+ concentration required for aerial mycelium formation in the culture medium ranged from 0.1 to 1.5 mM.
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Natsume et al. (1989) studied this question.
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