Key result
Consider post-cardiac injury syndrome for pleuritic chest pain, managed primarily with NSAIDs and colchicine.
Why the study?
Post-cardiac injury syndrome (PCIS) diagnosis is challenging in the Emergency Department and early detection is clinically relevant due to potential morbidity and mortality.
Post-cardiac injury syndrome (PCIS) encompasses inflammatory pericardial diseases resulting from cardiac injury, such as post-myocardial infarction, post-pericardiotomy, and post-traumatic pericarditis.
May prompt ED consideration of post-cardiac injury syndrome; leaves open prospective trials to validate NSAID-colchicine use.
The term post-cardiac injury syndrome (PCIS) defines a group of inflammatory diseases involving predominantly the pericardium.The syndrome results from a cardiac injury and refers mainly to post-myocardial infarction pericarditis, post-pericardiotomy syndrome and post-traumatic pericarditis (including iatrogenic conditions appearing after percutaneous interventions).Signs and symptoms are similar to those seen in acute pericarditis and pericardial effusion in other clinical settings.The diagnosis is clinical and could be challenging in the Emergency Department (ED).PCIS should be considered as an alternative diagnosis to acute pericarditis in case of unilateral right-sided, massive, or transudative pleural effusion.Although typically a benign condition, PCIS may result in significant morbidity and potential mortality; tamponade and constrictive pericarditis represent the leading complications.Therefore, early detection is clinically relevant.Currently, a combination of nonsteroidal anti-inflammatory drugs and colchicine is the mainstay treatment for this condition.Colchicine has also appeared to be effective in primary prevention of PCIS after cardiac surgery.The purpose of this article is to review the principle clinical characteristics of PCIS in order to achieve an early diagnosis.
No takes yet. Share an insight, caveat, or question.
Antonio Voza (2018) conducted a review in Post-cardiac injury syndrome (PCIS). NSAIDs and Colchicine was evaluated. Post-cardiac injury syndrome is an inflammatory condition that should be considered as a differential diagnosis for pleuritic chest pain in the emergency department, with NSAIDs and colchicine as the mainstay treatment.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: