Discussion Paper: Structural Studies of Rat Hemoglobins *

Since we are considering structural aspects of rodent hemoglobins, it seems appropriate to mention some studies on the hemoglobins of the rat.Rat hemoglobins are of particular interest because a severe anemia resembling thalassemia exists in the Belgrade strain.lBefore we could examine this strain, however, we first characterized the hemoglobins of normal adult Wistar animals. TABLE 2 PRIMARY SEQUENCE OF RAT I,H-Vala-Leu-Ser-ALa-Asp-Asp-Lys-Thr-Asn-Ile-Lys-Asn-Asn-Trp-G~y-15 L y s -I l e -G l y -G l y -H ~s -G l y -G l y -G l u -T y r -G l y -G l u -G l U -A l ~-L ~U -G ~~-3 0 Arg-~t-Phe-Ala-Ala-Phe-Pro-Thr-Thr-Lys