Population
Primary guinea pig embryo (GPE) fibroblasts
Comparison
Interferon induction using Newcastle disease… vs Overnight sample treatment at pH 2
Design
Preclinical
Authors
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May improve in vitro IFN yields from guinea pig cells; hypothesis-generating for production methods and leaves open broader applicability.
Guinea pig embryo fibroblasts can efficiently produce interferon when induced by specific viruses and processed with UV irradiation rather than pH 2 treatment.
Winship et al. (1983) studied this question.
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