Key result
A new mathematical model describes the effect of moderate physical activity on insulin-dependent and independent glucose utilization in healthy individuals and those with type 1 diabetes.
Why the study?
How does moderate physical activity affect insulin-dependent and insulin-independent glucose utilization in healthy individuals and individuals with type 1 diabetes?
How does moderate physical activity affect insulin-dependent and insulin-independent glucose utilization in healthy individuals and individuals with type 1 diabetes?
A new mathematical model describes the effect of moderate physical activity on glucose disposal, providing a potential tool to design safe and effective insulin therapies for type 1 diabetes.
May inform exercise-adjusted insulin dosing in type 1 diabetes; leaves open need for prospective validation.
Here, we present a new mathematical model describing the effect of moderate physical activity on insulin-mediated and noninsulin-mediated glucose disposal in subjects with and without diabetes. We believe that this represents a step-forward in the knowledge of type 1 diabetes pathophysiology, and an useful tool to design safe and effective insulin-therapies.
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ROMERES et al. (2021) studied this question. A new mathematical model describes the effect of moderate physical activity on insulin-dependent and independent glucose utilization in healthy individuals and those with type 1 diabetes.
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