Key result
Among patients undergoing transcatheter aortic valve replacement, 25.6% were discharged to a location other than home, which could be accurately predicted by a multivariable risk scoring model.
Why the study?
Patients undergoing TAVR are likely to be discharged to a location other than home, prompting evaluation of preoperative risk factors associated with non-home discharge.
Cohort (n=1,126)
Yes
A nomogram-based risk-scoring system using preoperative factors can accurately predict non-home discharge after TAVR, aiding in patient counseling and disposition planning.
Preoperative factors may inform TAVR discharge planning; leaves open nomogram validation and outcome impact before clinical adoption.
BACKGROUND: Patients undergoing transcatheter aortic valve replacement (TAVR) are likely to be discharged to a location other than home. We aimed to determine the association between preoperative risk factors and non-home discharge after TAVR. METHODS: Patients discharged alive after TAVR at three centers were identified from a prospectively maintained database randomly divided into 80% derivation and 20% validation cohorts. Logistic regression models were fit to identify preoperative factors associated with non-home discharge in the derivation cohort. Multivariable models were developed and a nomogram based risk-scoring system was developed for use in preoperative counseling. RESULTS: = 226) validation cohort. Mean ± SD age of the study population was 83 ± 8 years. In multivariable analysis, factors that were significantly associated with non-home discharge were extreme age, female sex, higher STS scores, use of general anesthesia, elective procedures, chronic liver disease, non-transfemoral approach and postoperative complications. The unbiased estimate of the C-index was 0.81 and the model had excellent calibration. CONCLUSIONS: One out of every four patients undergoing TAVR is discharged to a location other than home. Identification of preoperative factors associated with non-home discharge can assist patient counseling and postoperative disposition planning.
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Okoh et al. (2020) conducted a cohort in Inoperable aortic stenosis (n=1,126). Preoperative risk factors (e.g., advanced age, female sex, non-transfemoral approach) vs. Absence of risk factors was evaluated on Non-home discharge. Among patients undergoing transcatheter aortic valve replacement, 25.6% were discharged to a location other than home, which could be accurately predicted by a multivariable risk scoring model.
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