Sperm donation seems to be the only solution in cases of negative results with testicular sperm extraction (TESE). However, it implies a genetic dissociation between husband and offspring that results in psychological stress, as well as ethical and existential dilemmas for the couple. Facing these dilemmas, some couples prefer father-to-son donation as an alternative solution. However, father-to-son sperm donation involves many potential medical, ethical and emotional risks. A broad discussion within the scientific community on these issues should contribute towards a better approach of these cases.
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Nikos Nikolettos (2003) studied this question.
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