The preparation of a novel macrocyclic compound, tetrahydroxy[3.1.3.1]metacyclophane 5 by base-catalysed condensation of 1,3-(2,2′-dihydroxy-5,5′-di-tert-butyldiphenyl) propane 4 with formaldehyde in xylene in 90% yield is described and its conformational properties are discussed.
No takes yet. Share an insight, caveat, or question.
Yamato et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: