Evaluation of sufentanil sublingual tablet 30 mcg for perioperative pain management of in-office rhinology procedures

Effective analgesia for invasive office-based rhinology procedures can be challenging. While local anesthetics provide the basis for periprocedural analgesia, systemic opioids are often necessary for adequate pain control. We describe two patients successfully undergoing multiple painful rhinology procedures with the addition of a novel sufentanil 30 mcg sublingual tablet to our standard oral benzodiazepine and local anesthetic protocol. A sufentanil sublingual tablet administered preoperatively provided excellent analgesia throughout the duration of the procedure and was well tolerated. This new analgesic provides a rapid-acting alternative to standard oral opioid analgesics.