Postpoliomyelitis muscle pseudohypertrophy can be caused by adipose tissue replacement and work hypertrophy of muscle fibers.
Adipose replacement plus work hypertrophy may underlie postpoliomyelitis pseudohypertrophy; leaves open generalizability beyond this single case.
A 62-year-old patient who had had acute paralytic poliomyelitis in early childhood developed bilateral lower limb muscle pseudohypertrophy. The pseudohypertrophy was caused primarily by an enormous excess of adipose tissue replacing muscle fibers, and, in part, by work hypertrophy of muscle fibers.
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Bertorini et al. (1985) studied this question.
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