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Triiodothyronine (T3) has been conjugated to human serum albumin and injected into rabbits with the production of antibodies against T3. The serum from the rabbits was used in a double antibody radioimmunoassay for T3. The assay is sufficiently sensitive and specific for practical use in measuring T3 in serum.
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Gharib et al. (1970) studied this question.
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