The newly proposed ISI had been validated a small population of subjects different degrees of obesity and glucose (1). In a much wider sample obese subjects, the correlation of ISI clinical parameters related to insulin, such as low HDL cholesterol,, and hyperuricemia, similar to that of HOMA-IR, suggesting the 2 indexes could be similarly useful the identification of subjects with syndrome. its high correlation with-derived measures, the new index been proposed as a method for assessment insulin sensitivity in epidemiological
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Mannucci et al. (2000) studied this question.
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