Are There Any Associations Among Coagulation Factor VII Gene Polymorphism, Plasma Activated Factor VII Levels, and Cerebrovascular Disease?FVIIa (Ϫ43%), FVIIc (Ϫ24%), and FVIIag (Ϫ28%) than the homozygotes of normal 353R in each group.Thus, in Japanese, FVII R353Q polymorphism, which is more closely related to FVIIa levels than FVIIc or FVIIag levels, seems to have a less important influence on both silent and clinically overt cerebrovascular diseases.
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Kario et al. (2000) studied this question.
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