What question did this study set out to answer?

To assess the efficacy and anatomical patency of internal-mammary artery implantation for treating myocardial ischemia.

August 26, 1965New England Journal of Medicine

Internal-Mammary Implantation Operations for Relief of Myocardial Ischemia

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Design

Review

Authors

BBBruce J. BrenerNewark Beth Israel Medical Center RWRoderic WarrenSouth African Medical Research Council

Discussion

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Implication

Historical review of internal-mammary implantation underscores angiography for graft assessment; leaves open its role in modern revascularization research.

Key Points

To assess the efficacy and anatomical patency of internal-mammary artery implantation for treating myocardial ischemia.
Evaluated surgical implantation of the internal-mammary artery intended to revascularize ischemic myocardium.
Employed direct contrast substance injection into small vessels via selective coronary angiography to visualize arterial implant patency in vivo.
Subjective symptomatic relief occurred in patients despite anatomically unsuccessful procedures, emphasizing the unreliability of clinical symptoms alone.
Selective contrast angiography successfully demonstrated the anatomical patency of single arterial implants in vivo, overcoming past limitations in measuring coronary blood flow.

Structured PICO

Intervention

Internal-mammary implantation operations

Discusses the historical context and development of internal-mammary implantation operations for myocardial ischemia and the role of angiography in evaluating graft patency.

Cite This Study

Brener et al. (1965) studied this question.

synapsesocial.com/papers/6a88396e7b78edf2e3608e66 https://doi.org/10.1056/nejm196508262730905

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Implication

Historical review of internal-mammary implantation underscores angiography for graft assessment; leaves open its role in modern revascularization research.

Internal-Mammary Implantation Operations for Relief of Myocardial Ischemia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Internal-Mammary Implantation Operations for Relief of Myocardial Ischemia

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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