Copper sulfide (Cu 7 S 4 ) nanoparticles coated with an ultra-high payload (~5.0 × 10 7 fluorine atoms per particle) of fluorinated ligands (oleylamine functionalized 3,5-bis(trifluoromethyl)benzaldehyde, 19 F OAm ) exhibited a single intense 19F magnetic resonance (MR) signal and efficient near infrared photothermal performance in water medium. In vivo assessment revealed strong 19 F MR signals at cancerous lesions and effective inhibition of tumor growth after photothermal treatment, indicating the great potential of these fabricated nanoprobes for simultaneous 19 F MR imaging and photothermal therapy.
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Hu et al. (2016) studied this question.
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