Key result
Plasma sodium concentration was independently associated with subclinical left atrial enlargement in patients with Stage 3-5 chronic kidney disease (adjusted OR 1.29; 95% CI 1.14-1.47; P<0.001).
Cross-Sectional (n=261)
Odds Ratio: 1.29 (95% CI 1.14–1.47)
p-value: p=<0.001
Higher plasma sodium concentration is independently associated with subclinical left atrial enlargement in patients with moderate to severe non-dialysis chronic kidney disease.
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Supports sodium-LA link in non-dialysis CKD; hypothesis-generating and should not change practice.
Wang et al. (2013) conducted a cross-sectional in Stage 3-5 non-dialysis chronic kidney disease (n=261). Plasma sodium concentration was evaluated on Left atrial enlargement (LAE) (OR 1.29, 95% CI 1.14-1.47, p=<0.001). Plasma sodium concentration was independently associated with subclinical left atrial enlargement in patients with Stage 3-5 chronic kidney disease (adjusted OR 1.29; 95% CI 1.14-1.47; P<0.001).
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