Key result
Both cardiac troponin T and cardiac troponin I concentrations are elevated in patients with renal failure.
Cardiac troponin T and I concentrations are frequently elevated in patients with renal failure, which requires careful interpretation.
Requires careful troponin interpretation in renal failure to avoid misdiagnosis; leaves open assay-specific thresholds in CKD.
failure. 2 The elevation of blood cardiac troponin (cTn) concentrations in patients with kidney disease has variously been described as being an analytical false-positive: an example as to why cardiac troponin I (cTnI) was a superior test and to be due to re-expression of cardiac troponin T (cTnT) within the skeletal muscle. 3 Early work showed that both cTnT and cTnI concentrations are elevated in patients with renal failure, even using the relatively insensi
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Collinson et al. (2009) conducted a review in Renal failure. Cardiac troponins was evaluated. Both cardiac troponin T and cardiac troponin I concentrations are elevated in patients with renal failure.
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