Key result
Carotid artery atherosclerotic lesions were detected in 7.1% of 1,563 young railway workers under 45 years of age, with prevalence increasing from 0.95% in those aged 18-25 to 17.5% in those aged 41-45.
Why the study?
Cardiovascular diseases are leading in total mortality in Russia, prompting review of the role of endothelial dysfunction and early atherosclerotic changes.
Population
Young people (up to 45 years) undergoing professional examinations
Authors
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Supports early risk factor attention in young adults; leaves open whether carotid screening improves outcomes.
Endothelial dysfunction and associated biomarkers serve as early predictors of atherosclerosis, highlighting the importance of early risk factor modification, even in young populations.
Pizov et al. (2020) conducted a review in Atherosclerosis (n=1,563). Young age and endothelial dysfunction was evaluated on Prevalence of carotid artery atherosclerotic lesions. Carotid artery atherosclerotic lesions were detected in 7.1% of 1,563 young railway workers under 45 years of age, with prevalence increasing from 0.95% in those aged 18-25 to 17.5% in those aged 41-45.
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