Key result
Torque teno sus virus was highly prevalent in domestic pigs in Sichuan, China, with 83.2% of animals infected by either genogroup 1 or 2, and TTSuV2 being significantly more prevalent than TTSuV1.
Cross-Sectional (n=244)
Yes
TTSuV infection is highly prevalent and ubiquitous across domestic pig herds in Sichuan, China, with TTSuV2 being the dominant genogroup.
High TTSuV prevalence in Sichuan pigs supports herd surveillance; leaves open its role in porcine disease.
BACKGROUND: Torque teno sus virus (TTSuV), infecting domestic swine and wild boar, is a non-enveloped virus with a circular, single-stranded DNA genome. which has been classified into the genera Iotatorquevirus (TTSuV1) and Kappatorquevirus (TTSuV2) of the family Anelloviridae. A molecular study was conducted to detect evidence of a phylogenic relationship between these two porcine TTSuV genogroups from the sera of 244 infected pigs located in 21 subordinate prefectures and/or cities of Sichuan. RESULTS: Both genogroups of TTSuV were detected in pig sera collected from all 21 regions examined. Of the 244 samples, virus from either genogroup was detected in 203 (83.2%), while 44 animals (18.0%) were co-infected with viruses of both genogroups. Moreover, TTSuV2 (186/244, 76.2%) was more prevalent than TTSuV1 (61/244, 25%). There was statistically significant difference between the prevalence of genogroups 1 infection alone (9.4%, 23/244) and 2 alone (64.8%, 158/244), and between the prevalence of genogroups 2 (76.2%, 186/244) and both genogroups co-infection (18.0%, 44/244). The untranslated region of the swine TTSuV genome was found to be an adequate molecular marker of the virus for detection and surveillance. Phylogenetic analysis indicated that both genogroups 1 and 2 could be further divided into two subtypes, subtype a and b. TTSuV1 subtype b and the two TTSuV2 subtypes are more prevalent in Sichuan Province. CONCLUSIONS: Our study presents detailed geographical evidence of TTSuV infection in China.
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Mei et al. (2013) conducted a cross-sectional in Torque teno sus virus (TTSuV) infection (n=244). Torque teno sus virus (TTSuV) infection was evaluated on Prevalence of TTSuV infection. Torque teno sus virus was highly prevalent in domestic pigs in Sichuan, China, with 83.2% of animals infected by either genogroup 1 or 2, and TTSuV2 being significantly more prevalent than TTSuV1.
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