Key result
Two toddlers with human metapneumovirus infection presented with status epilepticus and respiratory failure, but fully recovered without sequelae over 2 weeks.
Case Report (n=2)
Human metapneumovirus infection may be associated with neurologic complications such as status epilepticus in pediatric patients.
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Alerts clinicians to possible hMPV-associated status epilepticus in toddlers; hypothesis-generating and should not change practice.
Human metapneumovirus (hMPV) is a relatively recent addition to the multiplicity of viruses causing respiratory illness in infants and children. Although well described in its ability to cause respiratory illness, there is limited data detailing the association of hMPV with neurologic complications. In this report, we describe 2 toddlers with hMPV infection who presented in status epilepticus and went on to develop respiratory failure. Both patients fully recovered over 2 weeks and were discharged from the hospital with no sequelae. The association between hMPV infection and neurologic complications is increasingly being reported in the literature. Clinicians should be aware of these uncommon manifestations of a common respiratory pathogen and consider testing for hMPV when managing pediatric patients who present with unexplained status epilepticus or encephalitis.
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Webster et al. (2014) conducted a case report in Status epilepticus and human metapneumovirus (hMPV) infection (n=2). Human metapneumovirus (hMPV) infection was evaluated on Clinical course and recovery. Two toddlers with human metapneumovirus infection presented with status epilepticus and respiratory failure, but fully recovered without sequelae over 2 weeks.
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