Key result
The mitral leaflet separation index strongly correlated with mitral valve area (r=0.95), and an MLSI >0.92 immediately after PMC effectively predicted an effective mitral valve area >1.5 cm2.
Why the study?
Does the mitral leaflet separation index accurately assess mitral valve area immediately after percutaneous mitral commissurotomy?
Observational (n=48)
Does the mitral leaflet separation index accurately assess mitral valve area immediately after percutaneous mitral commissurotomy?
Effect estimate: Correlation 0.95
The mitral leaflet separation index is a simple and effective method for assessing mitral valve area immediately after percutaneous mitral commissurotomy.
May simplify immediate post-PMC mitral valve assessment; hypothesis-generating and requires prospective validation before practice change.
The aim of this study was to determine the utility of the mitral leaflet separation index (MLSI), for determining the results of percutaneous mitral commissurotomy (PMC) in the acute setting, in the cardiac catheterization laboratory. Forty-eight patients undergoing PMC were studied and 96 examinations were performed. The overall correlation with the MLSI was 0.95. The mitral valve area (MVA) was determined by 2D echo planimetry (MVAPLM ) and 0.83 of the MVA was derived using Gorlin's formula (MVAGOR ). The MLSI was significantly different in patients with severe mitral stenosis (MS) (MVAPLM <1 cm(2) , MLSI of 0.70 mm) compared with those with mild MS (MVAPLM >1.5 cm(2) , MLSI of 0.92 mm). The MLSI is a simple and effective method for assessment of the MVA. An MLSI >0.92, immediately after PMC, had an excellent sensitivity and specificity for the prediction of an effective MVA of >1.5 cm(2) .
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Duggal et al. (2012) conducted an observational in Mitral stenosis (n=48). Mitral leaflet separation index (MLSI) vs. 2D echo planimetry and Gorlin's formula was evaluated on Correlation of MLSI with mitral valve area (Correlation 0.95). The mitral leaflet separation index strongly correlated with mitral valve area (r=0.95), and an MLSI >0.92 immediately after PMC effectively predicted an effective mitral valve area >1.5 cm2.
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