The conformational dependence of vicinal ¹³C¹³C spin–spin coupling constants in alicyclic compounds

A series of alicyclic compounds with dihedral angles of 0°, 60°, 90°, 120° and 180° between a 13 C‐labelled carbon atom and a carbon atom separated by three bonds from the label has been synthesized. The vicinal 13 C 13 C spin coupling constants were measured, and from the results a Karplus‐type relationship between 13 C 13 C spin coupling and dihedral angle is proposed.