A Case of Lung Cancer Developing in the Background of Progressive Massive Fibrosis

Pneumoconioses are parenchymal lung diseases caused by dust accumulation in the lungs and the resulting tissue reaction.A 60-year-old male patient was admitted to our clinic with complaints for 3 months of weakness, fatigue and constant pain in the right arm that did not change with movement.His professional history revealed employment in glazing processes in the ceramics industry for 28 years, while his medical history included pneumoconiosis and coronary artery bypass surgery in 2015.A recent postero-anterior chest X-ray had revealed increased opacity in the apical region of the right lung compared to a radiograph taken 3 years earlier.A highresolution thorax computed tomography of the lungs was performed revealing a 5 cm diameter mass lesion in the upper lobe of the right lung, although no differentiation between the mass and progressive massive fibrosis (PMF) could be made.Thoracic magnetic resonance imaging was performed after mass development was suspected on the basis of PMF, and a malignant lesion that was hyperintense compared to muscle and PMF tissue was observed in the apical segment of the right lung upper lobe on T2W images.No endobronchial lesion was observed in the patient on bronchoscopy, while a transthoracic biopsy performed on the hyperintense area was reported as adenocarcinoma.We present a case of PMF pneumoconiosis presenting with lung cancer.