Answers are grounded in this paper and cite their sources.
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease caused by the interaction of genetic susceptibility and environmental influences. There is increasing evidence that genes link to disease pathogenesis and heterogeneity by causing variation in protease anti-protease systems, defence against oxidative stress and inflammation. The main methods of genomic research for complex disease traits are described, together with the genes implicated in COPD thus far, their roles in disease causation and the future for this area of investigation.
No takes yet. Share an insight, caveat, or question.
Wood et al. (2006) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: