Over the last 10 years the structure of various human interferon-alpha (IFN-alpha) and interferon-gamma (IFN-gamma) subtypes was elucidated by combining protein chemistry and molecular biology. In this article some key studies related to the interferon structure are reviewed. The significance of the multiplicity of IFN-alpha and IFN-gamma subtypes is discussed in view of some current results.
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Menachem Rubinstein (1987) studied this question.
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