March 29, 1994Proceedings of the National Academy of SciencesOpen Access

Essential role for a heterogeneous nuclear ribonucleoprotein (hnRNP) in oogenesis: hrp40 is absent from the germ line in the dorsoventral mutant squid.

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Structured PICO

Population

Drosophila melanogaster (Oregon-R wild type and squid1 mutant flies)

Intervention

squid1 mutation (disruption of the squid gene encoding hrp40)

Comparator

Wild-type Drosophila melanogaster

Outcome

Expression and subcellular localization of hrp40 protein during oogenesissurrogate

The hnRNP protein hrp40 is essential for dorsoventral axis formation during Drosophila oogenesis and exhibits dynamic stage-specific cellular localization.

Discussion

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Implication

hrp40 requirement in follicle cells drives patterning; leaves open conservation in vertebrate oogenesis.

Cite This Study

Matunis et al. (1994) studied this question.

synapsesocial.com/papers/6a886d154231b321a876f82e https://doi.org/10.1073/pnas.91.7.2781

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Essential role for a heterogeneous nuclear ribonucleoprotein (hnRNP) in oogenesis: hrp40 is absent from the germ line in the dorsoventral mutant squid.

Structured PICO

Discussion

Implication

Cite This Study

Essential role for a heterogeneous nuclear ribonucleoprotein (hnRNP) in oogenesis: hrp40 is absent from the germ line in the dorsoventral mutant squid.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider