Poliomyelitis Vaccine Studies

112 children, comprising 27 boys (aged 8 to 10 years) at a training school and 85 children (aged 1 to 12 years) hospitalized for tuberculosis.

Poliomyelitis vaccine (Salk) administered intramuscularly as 3 injections (1.0 ml at 0, 1, and 5 weeks) or 2 injections (at 0 and 8-10 weeks). The group of 27 boys also received gamma globulin (0.28 ml per pound of body weight intramuscularly) 3 days prior to the first vaccine dose.

Children hospitalized for tuberculosis who received the poliomyelitis vaccine without prior gamma globulin administration.

Serum neutralizing antibody titers against poliomyelitis virus types 1, 2, and 3.surrogate