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April 11, 2012PLoS ONEOpen Access

Prevention of Wear Particle-Induced Osteolysis by a Novel V-ATPase Inhibitor Saliphenylhalamide through Inhibition of Osteoclast Bone Resorption

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AQAn QinTCTak Sum ChengZLZhen Lin

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Qin et al. (2012) studied this question.

synapsesocial.com/papers/6a88745edea5055e4b609a24https://doi.org/10.1371/journal.pone.0034132
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Also Consider

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  1. 1The Characterization of Cytokines in the Interface Tissue Obtained From Failed Cementless Total Hip Arthroplasty With and Without Femoral Osteolysis1994 · 227 citations
  2. 2Decreased Bone Resorption, Osteoclast Differentiation, and Expression of Vacuolar H+-ATPase in Antisense DNA-Treated Mouse Metacarpal and Calvaria Cultures <i>Ex Vivo</i>1999 · 9 citations
  3. 3Salicylihalamide A Inhibits the V0 Sector of the V-ATPase through a Mechanism Distinct from Bafilomycin A12004 · 118 citations
  4. 4Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of osteolysis.2007 · 64 citations
  5. 5Differential expression of transforming growth factor‐α and macrophage colony‐stimulating factor/colony‐stimulating factor‐1R (<i>c</i>‐<i>fms</i>) by multinucleated giant cells involved in pathological bone resorption at the site of orthopaedic implants2000 · 35 citations