Escherichia coli 15T(-) can initiate a cycle of deoxyribonucleic acid replication with equal efficiency in the presence of 25 or 50 mug of chloramphenicol/ml. However, these replication cycles are not completed in the presence of these drug concentrations, and the amount of replication decreases with increasing drug concentration.
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Karl G. Lark (1973) studied this question.
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