The Treatment of Adolescent Acne With Topical Application of Estrogens*†

ACNE vulgaris stands near the top of the list as one of the most common skin conditions seen by either the dermatologist or the general practitioner (1). Various authorities have estimated that it comprises approximately 15 per cent of all skin diseases (2, 3) and as such deserves our special attention. It is noted predominantly at adolescence (4). It is especially during this period that the boy or girl is psychologically least prepared for the disfigurement that this disease may bring. If the pathologic process is allowed to proceed, irreparable damage may be produced, not only to the skin but also as far as social adjustment is concerned. Although roentgen therapy is said to offer approximately an 80 per cent “cure,” many dermatologists feel that it is contraindicated before the age of 17. There have been numerous advocates of elimination diets, each author having his particular ideas as to what to avoid (5, 6, 7). The only other recognized medical management has been the use of kerolytic agents and the removal of the plugs from the follicular orifices (8). Some authorities feel still that the results in the treatment of acne continue to be somewhat discouraging.