Population
Cultured rat cardiac myocytes and fibroblasts
Design
Preclinical
Authors
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May implicate VEGF-MAPK signaling in myocyte stress responses; leaves open in vivo and clinical relevance.
VEGF rapidly activates the MAP kinase pathway in cultured rat cardiac myocytes, suggesting it may mediate cardiac responses to ischemic stress.
Seko et al. (1998) studied this question.
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