Plant materialMentha piperita leaves were purchased from a Peruvian supplier (Ayacucho, Perú).The samples were pulverized, and the powdered plant material (100g) was placed in a round-bottom flask containing 1000 ml of distilled water, which was then linked to ABSTRACTIntroduction: This study aimed to evaluate the anxiolytic effect of Mentha piperita essential oil on state and trait anxiety.Methods: The essential oil was extracted by hydrodistillation, and its chemical composition was analyzed using Gas Chromatography-Mass Spectrometry (GC-MS).A total of 93 participants were divided into a control group (CG) and an experimental group (EG), with 47 participants in the EG receiving MPEO aromatherapy and 46 in the CG.Anxiety levels were measured using the State-Trait Anxiety Inventory (STAI) at pretest and posttest phases.Results: GC-MS analysis showed that menthol had the highest concentration (42.56%), followed by menthone (19.24%) and linalool (11.68%).Mixed model analysis revealed that group assignment (EG vs. CG) was a significant predictor of posttest state anxiety (F=16.508,p=0.001) and trait anxiety (F=9.091,p=0.003), independent of pretest scores, supporting the intervention's effect on reducing anxiety.Posttest results showed a significant reduction in state anxiety in the EG compared to the CG (p=0.001) with a large effect size (r=0.508),while trait anxiety showed a moderate reduction (p=0.001,r=0.342).Conclusion: These findings suggest that Mentha piperita essential oil may effectively reduce state and trait anxiety, with a more pronounced impact on state anxiety.
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Alvarado-García et al. (2025) studied this question.
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