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April 12, 2010Arthritis & RheumatismOpen Access

Constitutive overexpression of BAFF in autoimmune‐resistant mice drives only some aspects of systemic lupus erythematosus–like autoimmunity

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Authors

WSWilliam StohlUniversity of Southern CaliforniaNJNoam JacobCedars-Sinai Medical CenterSGShunhua GuoIndiana University School of Medicine

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Stohl et al. (2010) studied this question.

synapsesocial.com/papers/6a88fbd86283353a7a18b787https://doi.org/10.1002/art.27502
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Increased CD4+Foxp3+ T Cells in BAFF-Transgenic Mice Suppress T Cell Effector Responses2009 · 101 citations
  2. 2The MHC Haplotype H2b Converts Two Pure Nonlupus Mouse Strains to Producers of Antinuclear Antibodies2009 · 12 citations
  3. 3BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth1999 · 1,340 citations
  4. 4In vivo staphylococcal superantigen-driven polyclonal Ig responses in mice: dependence upon CD4+ cells and human MHC class II2001 · 15 citations
  5. 5Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF2006 · 114 citations