-Response of high-grade osteosarcoma and Ewing sarcoma to preoperative chemotherapy can significantly affect the surgical approach to patients with these tumors and their disease-free survival. This article presents the findings and limitations of different imaging modalities (radiography, angiography, sonography, scintigraphy, and magnetic resonance [MR] imaging and spectroscopy) for evaluating this chemotherapeutic response. Particular emphasis is given to the currently most effective modality-dynamic contrast-enhanced MR imaging. KEYWORD Bone, neoplasms - osteosarcoma - chemotherapy - Ewing sarcoma - magnetic resonance (MR) - rapid imaging
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Shapeero et al. (2000) studied this question.