Why the study?
Are APOE and BIN1 gene polymorphisms associated with Alzheimer disease in a Turkish population?
Population
109 individuals (53 Alzheimer disease patients and 56 controls) from a Turkish population
Comparison
Assessment of APOE alleles and BIN1 gene… vs Controls without Alzheimer disease
Design
Case-control
Authors
Loading...
APOE E4 may inform AD risk assessment in Turkish patients; leaves BIN1 role open and requires replication.
Are APOE and BIN1 gene polymorphisms associated with Alzheimer disease in a Turkish population?
In a Turkish population, the APOE E4 allele is strongly associated with Alzheimer's disease, whereas BIN1 gene polymorphisms are not.
Kaya et al. (2015) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: