The text that follows reviews and discusses the papers published in the Journal on chronic obstructive pulmonary disease (COPD) during 2011. Whenever relevant, works published earlier or elsewhere are included. The reader is referred to the original papers for further details. We have organized the review according to the following subheadings: Risk Factors, Natural History, Physiology, Disease Mechanisms, Phenotypes and Biomarkers, Comorbidities, Management, and Exacerbations.
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Agustí et al. (2012) studied this question.
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