What question did this study set out to answer?

To identify the prevalence and lineage distribution of human papillomavirus (HPV) genotypes among women in South Andaman Island.

August 25, 2023DiagnosticsOpen Access

Distribution of Human Papillomavirus Genotypes among the Women of South Andaman Island, India

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Cross-sectional study uncovers high-risk human papillomavirus genotypes in women, highlighting the urgent need for targeted vaccination.

To identify the prevalence and lineage distribution of human papillomavirus (HPV) genotypes among women in South Andaman Island.
Conducted a cross-sectional study analyzing cervical scrape samples collected from women (N=1000) with written informed consent.
Detected HPV genotypes using PCR assays and performed molecular evolutionary sequencing analysis via MEGA11 to classify lineages.
Identified high-risk HPV 16 in 32 samples and HPV 18 in 4 samples, with 15 distinct genotypes detected overall and multiple genotypes present in 6 cases.
Determined that HPV 16 was the most prevalent genotype (predominantly Lineage-A, sub-lineage A2), while HPV 18 belonged to lineages A1 through A5.
Observed the co-circulation of HPV-16 sub-lineages A1, A2, and D1, differing from the globally predominant A1 strain.

Parvez et al. (2023) studied this question.

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