The described underwater fiber-optic sensing system allows for dynamic force measurement of striated muscle myofibrils at the microgram level.
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Enables microscale myofibril force assays in vitro; leaves open translation to in vivo cardiac research.
We describe a system for measurement of the dynamic mechanical properties of small bundles of myofibrils of muscle. Underwater fiber-optic sensing of tension via displacement of a quartz beam has been accomplished with a noise level of about 100 nanoNewtons in a bandwidth of 1 to 40 Hz.
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Thorson et al. (1975) studied this question.
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