Why the study?
What are the mechanisms of action of ACE inhibitors and their implications for hemodynamic stability during anesthesia?
Population
Patients treated with angiotensin-converting enzyme inhibitors (ACEIs) undergoing anesthesia
Design
Review
Authors
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Supports vigilance with vasopressors and fluids in hypovolemic ACEI patients at induction; leaves open optimal perioperative protocols for prospective trials.
What are the mechanisms of action of ACE inhibitors and their implications for hemodynamic stability during anesthesia?
Patients on ACE inhibitors are at risk for severe hypotension during anesthesia induction, requiring anesthesiologists to be prepared with vasopressors and fluids.
Behnia et al. (2003) studied this question.
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